Literally meaning: “entirely male”
Origin: Anc Greek
όλος/holos(= whole, entire, all)
ανδρός/andros(=genitive case of noun ανήρ/aner=man, male)
In 1922 by Enriques in order to describe a type of inhetritance in which all males are affected and in which females neither exhibit the trait nor transmit the underlying gene.( Source:
Enriques P, 1922. Hologynic heredity. Genetics 7: 583-589.
Y-linked nonhomologous genes or loci that can only be transmitted from father to son.