Origin: Anc Greek
όλος/holos(= whole, entire, all)
ένζυμο/enzymo(=enzyme) > εν/en(=in) + ζύμη/zime(= leaven)
The term “Enzyme” was coined by F.W Kuhne (1837 - 1900) in 1978.
The complete enzyme consisting of an apoenzyme (protein component of an enzyme) combined with its cofactor (a non-protein chemical compound).