Literally meaning: “before the phage”
Origin: Anc Greek
προ-/pro-(= towards, in front of, precede)
+ φάγος/phagos(=eater) > έφαγον/ephagon(=indefinite tense of verb "εσθίω"/esthio(eat, devour)
In 1952 by Andre Lwoff (1902-1994). Lwoff was awarded the Nobel Prize in physiology or medicine (1965), along with Francois Jacob and Jacques Monod for his finding that the genetic material of a virus can be assimilated into bacteria.
A prophage is the latent stage of a phage in a bacteriuma phage in which viral genome inserted and integrated into the circular bacterial DNA chromosome.