Literally meaning: “in front of thrombin”
Origin: Anc Greek
πρo-/pro-(prefix denoting “in front of”, “towards”)
+θρομβίνη/thrombin(=thrombin, a blood coagulation factor, cleaving fibrinogen to form fibrin in the last step of coagulation cascade) > θρόμβος/thrombos(=clot) >θρέφω/threpho(=feed)
Prothrombin (factor II) is a plasma glycoprotein that is converted to thrombin in the presence of thromboplastin and calcium ion during coagulation cascade (blood clotting).