Term: lyase
Literally
meaning: “enzyme
of breaking down”
Origin: Anc Greek
λύω/leo =break down, solve, loose, degradate)
+-άση/-asy(=-ase) enzyme suffix added to the
name of the substrate that the enzyme
hydrolyzes eg proteinase for protein or lipase for lipids
>διά-/dia-(=prefix denoting “through”, “apart” )
> δυο/dio(two) + στάσις/stasis(=halt)
> ίστημι/histimi(=stand).
Coined/History
(?)
Definition
A lyase is an enzyme that
catalyzes the breaking of various chemical bonds by means other than hydrolysis
and oxidation forming usually a double bond, or that conversely add groups to
double bonds. The reverse process is performed by synthetase
(ligase).
which is an example of a lyase cleaving carbon-carbon bonds. Lyase works without the necessary requirements for cofactor recycling and gives an absolute stereospecificity with a theoretical yield of 100%, lyase introduction
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