angiogenesis

Term: angiogenesis

Literally meaning: “production of new vessels”

Origin: Anc Greek

αγγείο/aggio (=vessel, receptacle) >  άγγος/aggos(=tube)

+γένεσις/genesis(=origin) > γεννώ/geno(= “to produce”, “to give birth to”, “to create”)

Coined/History

The term angiogenesis was coined by Arthur T. Hertig in 1935 to describe the formation of new blood vessels in the placenta.

Source

Hertig AT. Angiogenesis in the early human chorion and in the primary placenta of the macaque monkey. Contr Embryol Carnegie Inst. 1935;25:37–81.

Definition

Angiogenesis is the process of new vessels formation from pro-existing vessels  induced by angiogenic factors.  Angiogenesis is opposite to angiostasis (normal regulation of blood vessels) and includes proliferation and migration of endothelial cells. Vasculogenesis includes de-novo formation of new vessels.