Term: actin
Literally
meaning: “ ray”
Origin: Anc Greek
'áκτίς, -[éνος/ actis(=ray) > (genitive) ακτίνος/actinos
+(-ίνη)/-in, chemical ending that forms feminine nouns such
as feminine French suffix: –ine)
Coined/History
Actin was extracted first time from muscle by British
physiologist W.D.Halliburton (1860-1887), in 1887. The protein was isolated in
a pure form in 1942 by Hungarian Bruno F Straub (1914-1996) and named as actin
by Szent-Gyorgyi (1893-1986) in 1945. Szent-Gyor gyi
demonstrated that actin with myosin are responsible for muscular contraction,
and showed that the ATP is the immediate source of energy in muscle
contraction.
Source
Halliburton, W.D. (1887). “On muscle p[lasma” J Physiol. 8 (3-4): 133.
Szent-Gyorgyi, A. 1945. “Studies on muscle.” Acta
Physiol Scandinav 9
(suppl. 25)..
Definition
Actin is a globular (42-kDa) and highly-conserved
protein found alma s t
in all eukaryotic cells. Actin is the monomeric subunit of microfilaments and
thin filaments playing a major role in many cellular processes such as
cytokinisis, cell molity and muscle contraction.
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