Term: troponin
Literally
meaning: “that which is turned”
Origin: Anc Greek
+-τρόπος/tropos(=suffix
denoting way, habit, direction or tendency) >τρέπω/trepo(=turn)
Coined/History
In 1965 a protein was found which promoted aggragation
of tropomyosin. In 1968, it was determined that this protein which named troponin,
was a complex of at least two different protein factors (Ebashi and Kodama) and
finally in 1971 troponin was purified for first time (Ebashi et al, 1971).
Definition
Troponin is a complex of three calcium-regulated proteins (troponin C, troponin I andtroponin T) that affects tropomyosin to abolish its sites
for actin and allowing the muscle contraction.
Troponin is found on the thin filaments within the sarcomere of all
types of striated muscle.
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