Literally meaning: “excess of protein”
Origin: Anc Greek
παρά-/para-(=pefix denoting intentification, “beside”, “near”, “contrary of” “side by side” “past by”, “beyond”)
+πρωτεΐνη/proteini(=protein) > πρώτος/protos(=first or of prime importance)
In 1940 to describe the the abnormal proteins that are produced by myeloma cells, the earliest described tumor markers.
Paraprotein (or monoclonal antibodies in the plasma) is the incomplete immunoglobulin that is produced in a pathological condition as in multiple myeloma.