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gyrase


Term: gyrase
Literally meaning: “the enzyme that breaks down rounds
Origin: Anc Greek
γυρός/gyros(=round, curved)
+(-άση)/(-asy)(=-ase) enzyme suffix added to the name of the substrate that the enzyme  hydrolyzes eg proteinase for protein or lipase for lipids
>διά-/dia-(=prefix denoting “through”, “apart” )
> δυο/dio(two) + στάσις/stasis(=halt) > ίστημι/histimi(=stand).
Coined/History 
DNA  gyrase  was  discovered  and  first  isolated  by  Gellert  et
al.  from  E.  coli.  It  has  been  further  studied  by  this  and
other  groups  and  has  also  been  isolated  from  Micro-
coccus  Zuteus.
Sourse
Gellert,  M.,  Mizuuchi,  K.,  O’Dea,  M.  H.,  and  Nash,  H.  (1976) Proc.  Natl.  Acad.  Sci.  U.  S. A.  73,  3872-3876
Definition
Gyrase is the enzyme that unwinds the coiled  double-stranded DNA in order to relieve tension for helicase.

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