Literally
meaning: “pertaining
to birds”
Origin: Anc Greek
όρνις/ornis(=bird) > όρνυμι /ornymi(=stand
up, rise, stimulate)
Coined/History
In 1877 chemist Jaffe isolated ornithine from
ornithuric acid which was discovered in the urine of birds.
(Jaffe, M.
1877 Uber das Verhatten der Benzoesaure im organismus der
Vogel. Beri.Deutsch. Chem. Gesellsch., 10: 1925).
Definition
 |
| ornithine |
L-ornithine is an important part of urea cycle in
order to dispose of excess nitrogen as it is the result of breakdown of L-arginine after the action of enzyme arginase. Ornithine also helps for formation of
aminoacids : proline, glutamic acid and citrulline.
Ornithine is also one of 4 amino acids which together synthetically mimic the action of hGH (human growth hormone) offering the extension of life, as Dr Dan'l Rudman of the Univ of Wisconsin showed in 1990, when the pituitary posterior lobe stops emitting the stuff in natural aging. -- Dr Andrew Tempelman
ReplyDeleteL-Ornithine is a non-essential amino acid, metabolized to generate L-arginine, which is further incorporated into proteins. α-Ketoglutarate is a key intermediate in the Krebs cycle, coming after isocitrate and before succinyl CoA. Acting as a co-substrate, α-Ketoglutarate also plays important function in oxidation reactions involving molecular oxygen. L-Ornithine α-Ketoglutarate Monohydrate
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