Literally meaning: “dissolution of the sugar”
Origin: Anc Greek
γλυκός/glycos(=sweet) as glycose, an older term for glucose
+λύσις/lysis(=dissolution, degradation > verb λύω/leo =break up, solve, loose, degradate)
In 1897 Buchner found by accident that yeast extracts could convert sucrose to ethanol proving that fermentation could occur outside living cells. Seven years later, (1905) William Young discovered that the rate of fermentation decreased without the addition of phosphate (Pi). By 1940 all of the vreactions of the glycolysis pathway were known from the research of Embden, Meyerhof, Parnas and Warburg.
Glycolysis is the anaerobic catabolism of glucose that takes place in the cytoplasm and converts glucose (C6H12O6), into pyruvate (CH3COCOO− + H+). producing four ATP molecules and two NADH2+ molecules.