Literally meaning: “ ray”
Origin: Anc Greek
'áκτίς, -[éνος/ actis(=ray) > (genitive) ακτίνος/actinos
+(-ίνη)/-in, chemical ending that forms feminine nouns such as feminine French suffix: –ine)
Actin was extracted first time from muscle by British physiologist W.D.Halliburton (1860-1887), in 1887. The protein was isolated in a pure form in 1942 by Hungarian Bruno F Straub (1914-1996) and named as actin by Szent-Gyorgyi (1893-1986) in 1945. Szent-
demonstrated that actin with myosin are responsible for muscular contraction,
and showed that the ATP is the immediate source of energy in muscle
Halliburton, W.D. (1887). “On muscle p[lasma” J Physiol. 8 (3-4): 133.
Szent-Gyorgyi, A. 1945. “Studies on muscle.” Acta Physiol Scandinav 9 (suppl. 25)..
Actin is a globular (42-kDa) and highly-conserved protein found
in all eukaryotic cells. Actin is the monomeric subunit of microfilaments and
thin filaments playing a major role in many cellular processes such as
cytokinisis, cell molity and muscle contraction. almas