Literally meaning: “binding protein”
Origin: Anc Greek
δέω/theo(=to bind) > δεσμός/desmos(=bond)
Desmin is a protein of vertebrates first described in 1976, and purified in 1977
Desmin is a 52kD protein that is subunit of intermediate filament found near the Z line in sarcomere of muscle. It is encoded by DES gene mutations of which cause myopathy myofibrillar type 1 (MFM1) or desmin-related myopathy (DRM) .