Term: angiogenesis
Literally
meaning: “production
of new vessels”
Origin: Anc Greek
αγγείο/aggio (=vessel, receptacle) > άγγος/aggos(=tube)
+γένεσις/genesis(=origin)
> γεννώ/geno(= “to produce”, “to give birth to”, “to create”)
Coined/History
The term angiogenesis was coined by Arthur T.
Hertig in 1935 to describe the formation of new blood vessels in the placenta.
Source
Hertig AT. Angiogenesis in the early human chorion and in the
primary placenta of the macaque monkey. Contr Embryol Carnegie Inst. 1935;25:37–81.
Definition
Angiogenesis is the process
of new vessels formation from pro-existing vessels induced by angiogenic factors. Angiogenesis is opposite to angiostasis
(normal regulation of blood vessels) and includes proliferation and migration
of endothelial cells. Vasculogenesis includes de-novo formation of new
vessels.
